Epidemiology Research Paper Example | Topics and Well Written Essays - 1750 words

Epidemiology - Research Paper Example (Friis and Sellers, 2009). Epidemiological activity is used since many decades. The statistical tools are the most powerful device used for identifying the risk factors and the relationship between various factors such as environmental factors, drugs, genetics, hormones, occupation, nutrition and viruses, bacteria. It was the epidemiological studies that revealed the relationship between Human Papilloma Virus (HPV) and cervical cancer. (Friis and Sellers, 2009). The US centre for Disease Control and Prevention [CDC] estimates that most of the new cases of HPV are teens and young adults. They have estimated that 6 million new cases are recorded every year in US. In 2007, the CDC has announced that one among the four teenage girls ages 13 to 19 are having HPV. Among the teens, 40 percent of the children who had sex were found to have Human papilloma virus. (Lyon and Antoniades, 2009). Similarly CDC has also found that 20 Americans are infected with the HPV and many of them are not awar e of it. Uses of Epidemiology 1. To study the history of the disease and the changes in the disease states. It also helps to study the history of the healthy populations in the locality. 2. To measure the true dimension of the disease and the healthy individuals. The prevalence of the disease based on the risk factors, the distribution of disability and mortality can be understood using epidemiological studies. 3. ... (Friis and Sellers, 2009). 6. To identify the root of the chronic diseases and provide the complete history of the diseases to help the practitioners and people eradicate the disease from the epidemic regions. 7. To confirm the risk factors and causes of the disease using the knowledge obtained through studies for the risky and multiple causative disease. (Friis and Sellers, 2009). Human Papilloma virus: Papilloma viruses are DNA viruses that infect epithelia causing a variety of lesions, warts and carcinoma. Human Papilloma viruses (HPV) are ubiquitous in nature causing cervical and other anogenital cancers. HPV infections are most common in the young and sexually active people within the age limit of 20 – 24. Human papilloma viruses form two groups; Genital and cutaneous HPVs. Most of the papilloma viruses are host specific. Human papilloma virus has an icosahedral symmetry with 72 capsomers arranged in the pentameric structure. It has a circular double stranded DNA of 8 kb long. It has three types of genes: early genes, late genes and control genes. HPV first infects the basal epithelium and inserts itself into the cell. It then dissociates and produces low copy number episomes. The HPV gets loosely linked to the keratocyte differentiation and divides as the keratinocyte undergoes differentiation. The major oncogenic proteins involved in the HPV carcinogenesis are E6 and E7 which interfere in the cell cycle control mechanisms. E6 on binding with the cellular protein AP, degrades the p53 through ubiquitin- directed proteolysis. P53 is essential for DNA repair, when this molecule is degraded; it affects the ell cycle control. The result is genetic instability and accumulation of the mutants

Research Training Programme Project Essay Example | Topics and Well Written Essays - 3000 words

Research Training Programme Project - Essay Example Future analysis of this panel could be effected by correcting the mistake. Additionally, only two years of the four year programme was utilized, as the other two years could not provide an adequate percentage of the data. The importance of this data cleaning should be considered when the final results are analysed. Cleaning is a judgmental process which sometimes removes items which are of great importance to those providing the data. Only by repeating the data collection can any factors which occur again and again be noticed. This paper is based upon research done by Loughborough University as part of a review of the Business School's Training Programme. This research was conducted over a number of weeks at the beginning of 2006, and a survey was conducted amongst former students, questioning them about their experiences and opinions of the course. The intention of the questionnaire was to discover whether the students had benefited from the course, and whether they felt that the teaching was adequate. As this was a group working, there were a number of meetings throughout the weeks to try and ensure co-operation and agreement amongst all the members. After a series of meetings and interviews in January, the questionnaire was sent out to students in March, and received back in April. This data was then input into a SPSS program, from which the results in this paper are taken. At the design meetin... From these results we will need to conduct an analysis to try and find some significant results. Why that use of design THE NATURE OF THE QUESTIONNAIRE The questionnaire that was sent to the students was divided into five sections, each dealing with a different topic. In the first section, for example, the questions concerned the personal details of the student, age, nationality and so on. In the second section, we asked them about the relevance of certain topics to their research. The third topic concerned the usefulness of the training programme; the fourth dealt with improvements to the student's relationships, and the fifth and final section asked the students to rate their satisfaction with the course. The design of this questionnaire was to enable us to demonstrate whether the training programme met the students' requirements, whether it improved their interpersonal relationships, and whether they felt the course had proved satisfactory. The first section allowed the students to be readily quantified and compared, which can prove useful when considering results, the other sections concentrate upon the courses, and the benefits and satisfaction the students felt that they had gained. . Other aspects of these results may become significant when we are comparing the results via SPSS. As the aim of this project is to improve the teaching of business courses at Loughborough, then consideration of the benefits to the students, and the improvements in their relationships, must be included while analyzing their satisfaction. Analysis The analysis of this questionnaire was conducted using the SPSS system of statistic management. This programme provides the analyst